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arXiv:cs.LG· Guang Yang, Fengchen Liu·· 5 小时前AI 评分25

GenoTrace:面向基因组基础模型蒸馏的可继承水印

GenoTrace: Inheritable Watermarks for Genome Foundation Model Distillation

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GenoTrace 是一种密码学与机器学习交叉的水印方法,通过密码子位置和物种特异性密码子用法两个 token 级因子调制教师模型的生成偏置,使学生模型输出可被审计。

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Abstract:Can a genome model retain a detectable record of the synthetic sequences used to train it? We study watermark inheritance through distillation with GenoTrace, a codon-aware extension of green-list watermarking. Two token-level factors modulate the teacher's generation bias using codon position and organism-specific codon usage. The resulting sequences train a smaller student, whose outputs are audited without an active watermark processor. In a three-seed GenomeOcean-500M-to-100M experiment, the joint configuration achieves a mean audit score of 17.88 and 94.5% detection at a fixed threshold. It retains 49.0% detection after key-aware token substitution, compared with 0% for the available single-seed plain-watermark comparator, and 47.0% after combined mechanism-targeted nucleotide edits. Additional experiments establish inherited signal across five organism-conditioned datasets and teacher-student size ratios up to 40. Component ablations and computational sequence-quality assays reveal distinct operating points for detection strength and coding coverage. GenoTrace provides a practical token-level construction and an empirical account of how genomic structure shapes inherited watermark signals. The findings concern shared-tokenizer distillation and the tested editing procedures, with calibration and biological utility treated as separate evaluation requirements.
Comments: Withdrawn by the authors pending an institutional intellectual property review
Subjects: Cryptography and Security (cs.CR); Machine Learning (cs.LG); Genomics (q-bio.GN)
Cite as: arXiv:2609.35881 [cs.CR]
  (or arXiv:2609.35881v2 [cs.CR] for this version)
  https://doi.org/10.48550/arXiv.2609.35881

arXiv-issued DOI via DataCite

Submission history

From: Guang Yang [view email]
[v1] Sun, 27 Sep 2026 00:15:38 UTC (1,512 KB)
[v2] Thu, 1 Oct 2026 22:13:43 UTC (1 KB) (withdrawn)

来源:arXiv:cs.LG · arxiv.org